Acetyl-L-Carnitine - also known as MRM, Methylation, and ALCAR - is a natural remedy antioxidant that specifically benefits the brain. ALCAR helps supply the brain with energy by improving function in the mitochondrion, the cell’s energy generator. ALCAR promotes effective use of acetylcholine, a key neurotransmitter for brain and nerve function. Acetyl-L-Carnitine has been shown in clinical studies to benefit cognitive ability, memory and mood.
There are Many Scientific Evidence and Facts for Acetyl L-Carnitine.
Acetyl L-Carnitine and Angina
In one controlled study, 200 individuals with angina (the exercise-induced variety) took either 2 g of L-Carnitine daily or were left untreated. All participants continued to take their usual medication for angina. Those taking Carnitine showed improvement in several measures of heart function, including a significantly greater ability to exercise without chest pain. They were also able to reduce, or eliminate, the dosage of some of their heart medications as their symptoms decreased.
Another double-blind, placebo-controlled trial tested L-Carnitine in 52 individuals with angina, and found evidence of benefit. In addition, several small studies (some of them double-blind) tested Propionyl-L-Carnitine for the treatment of angina, and also found evidence of benefit.
Acetyl L-Carnitine and Hardening of The Arteries (Artherosclerosis)
People with advanced hardening of the arteries, or atherosclerosis, often have difficulty walking due to lack of blood flow to the legs. Although Carnitine does not increase blood flow, it appears to improve the muscle’s ability to function under difficult circumstances. Adding Acetyl L-Carnitine to COR-Resotor’s Nitric Oxide, anti-aging, vasodilation formula, only makes good health sense.
A 12-month double-blind, placebo-controlled trial of 485 patients with intermittent claudication evaluated the potential benefits of Carnitine. Participants with relatively severe disease showed a 44% improvement in walking distance as compared to placebo. However, no improvement was seen in those with mild disease. Another double-blind study followed 245 people and also found similar benefit.
Similar results have been seen in most but not all other studies of L-Carnitine or Propionyl-L-Carnitine.
Acetyl L-Carnitine – Congestive Heart Failure
Several small studies have found that Carnitine can improve symptoms of congestive heart failure. In one trial, benefits were maintained for 60 days after treatment until the Carnitine was stopped.
Acetyl L-Carnitine After a Heart Attack
Carnitine can help reduce death rate after a heart attack. In a 12-month placebo-controlled study, 160 individuals who had experienced a heart attack received 4 g of L-Carnitine daily or placebo, in addition to other conventional medication. The mortality rate in the treated group was significantly lower than in the placebo group, 1.2% versus 12.5%, respectively. There were also improvements in heart rate, blood pressure, angina (chest pain), and blood lipids. A larger double-blind study of 472 people found that Carnitine can improve the chances of survival if given within 24 hours after a heart attack. Note: Carnitine is used along with conventional treatment, not as a substitute for it.
Acetyl L-Carnitine – Chronic Obstructive Pulmonary Disease (COPD)
Evidence from three double-blind placebo-controlled studies that each tested 49 patients suggests that L-Carnitine can improve exercise tolerance in COPD, presumably by improving muscular efficiency in the lungs and other muscles. Adding NAC (N Acetyl Cysteine) to COR-Restor along with the Acetyl L-Carnitine can have a dramatic impact on those who suffer from COPD and other lung impairment issues.
Acetyl L-Carnitine and Mild Depression
A double-blind study of 60 seniors with mild depression found that treatment with 3 g of Carnitine daily over a 2-month period significantly improved symptoms as compared to placebo. Positive results were seen in another study as well.
Acetyl L-Carnitine and Hyperthyroidism
Enlargement of the thyroid (goiter) can be due to many causes, including cancer and iodine deficiency. In some cases, thyroid enlargement occurs without any known cause.
Treatment of benign goiter generally consists of taking thyroid hormone pills. This causes the thyroid gland to become less active, and the goiter shrinks. However, there may be undesirable effects as well. Symptoms of hyperthyroidism (too much thyroid hormone) can develop, including heart palpitations, nervousness, weight loss, and bone breakdown.
A double-blind, placebo-controlled trial found evidence that use of L-Carnitine could alleviate many of these symptoms. This 6-month study evaluated the effects of L-Carnitine in 50 women who were taking thyroid hormone for benign goiter. The results showed, Carnitine taken daily protected participants’ bones and reduced other symptoms of hyperthyroidism.
Finally, Acetyl L-Carnitine may delay the aging process. Of course we all grow older, but there is a big difference in GETTING older and GROWING old.
Lipoic Acid Complements Acetyl L-Carnitine
Our team of world class formulators, doctors, and physiological experts, at In Good Health, Inc. have gone the extra mile. Most of us are “baby boomers,” and our generation does not mind GETTING older, we just don’t want to GROW old.
Our team has combined alpha lipoic acid, “the antioxidant’s antioxidant, with Acetyl L-Carnitine, for the greatest ANTI-aging formula of all.” This remarkable fatty acid is a potent antioxidant that also regenrates Glutathione, which is the mitochondria’s number one defender.
Numerous studies have been conducted on the use of lipoic acid as therapy for diseases associated with type 2 diabetes and heart disease. They emphasize that there is a significant age-related mitochondrial decay in heart cells and that either ALC or lipoic acid can ameliorate this decay independently. Because of the complementary nature of the effects of these two agents on mitochondria, however, some scientists recommend that they be taken together.